
WORKSTATION MOTHERBOARD
ASUS Pro Workstation motherboards are designed for professionals in AI training, deep learning, animation, 3D rendering or media production. Featuring expandable graphics, extensive storage, impressive connectivity and exceptional overall performance and reliability, Pro Workstation motherboards are the ideal solution for creative professionals. Each motherboard includes centralized management software with support for out-of-band management, so they're also an efficient and cost-effective option for IT administrators.

USB BIOS
Flashback®
Dual Intel®
2.5G LAN
2 x USB 3.2 Gen2
(1x Type-A &
1x Type-C)
8CH Audio with
DTS support
PCI-E Gen3 x16
(x16 Link)
PCI-E Gen3 x16
(x8/0 link)
PCI-E Gen3 x16
(x16/x8 link)
PCI-E Gen3 x16
(x8/0 link)
PCI-E Gen3 x16
(x16/x8 link)
PCI-E Gen3 x16
(x8/0 link)
Crystal Sound3
PCI-E Gen3 x16
(x16/x8 link)
DIGI + Power Control
LGA 2066 Sockets for Intel® Core™ X-series processors
3 x U.2 ports
8 x DDR4 4266 MHz (O.C.) support
1 x vertical M.2, up to 22110
ASUS SafeSlot
ThunderboltEX 3 card header
8 x SATA3 6Gb/s ports
1 x M.2, up to 2280
Breakthrough Performance
Intel®'s high-end desktop platform raises the stakes with updated Intel Core™ X-Series Processors that boast cores, cache, and bandwidth. The Pro WS X299 Sage II is ready for the additional processing power that plows through CPU-intensive tasks, and the extra bandwidth allows you to add more GPUs and NVMe SSDs to accelerate a wide range of work.
- Multi-GPU support
- Memory
- Connectivity
- Storage
Four Dual-slot GPUs support
Pro WS X299 Sage II fits up to four dual-slot graphics cards and supports both NVIDIA® SLI™ and AMD CrossFire™ 4-way configurations to enable multi-GPU setups that harness the full power of the latest graphics technologies, including NVIDIA® Quadro®. NVIDIA® Quadro® is the perfect complement to Pro WS X299 Sage II, delivering the best performance for design, modeling, medical research, and processing-intensive simulation and rendering applications.
CPU 48/44 Lane & CPU 28 Lane
4-Way/3-Way/2-Way

Back to Breakthrough Performance
Tune it your way
Comprehensive controls form the foundation of the ASUS X299 motherboards. The Pro WS X299 Sage II packs flexible tools to tune every aspect of your system to deliver the performance that you desire.
Overclock CPU
Auto Tuning
4.9G
Default
3.0G
CPU : Intel LGA 1151 i9-10980XE | Motherboard : Pro WS X299 Sage II
DRAM : CORSAIR CMK32GX4M4E4133C19R Ver. 4.31 |
Power : Delta DPS-1200QB | Water-cooling : Bitspower SC6 PWM | OS: Windows 10
- AI overclocking
- 5-Way Optimization
AI Overclocking
ASUS AI Overclocking makes automatic tuning faster and smarter than ever before. Available in Windows or directly through the UEFI, it profiles the CPU and cooling to predict the optimal configuration for each individual system.

CPU Potential
A proprietary algorithm evaluates the capabilities of your CPU
![]()

Cooling Capability
Onboard intelligence watches system vitals such as temperature, fan speed, and power draw to gauge cooling performance

5-Way Optimization
One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.
An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
Fans stay quiet as a whisper for everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.
All-new stress test that allows users to optimize and overclock for CPU or memory-centric workloads.

TPU Insight

EPU Guidance

Fan Xpert 4

Digi+ Power
Control

Turbo Core
App
CPU performance boost
The TurboV Processing Unit (TPU) is the intelligence behind our automated system-tuning utility, offering the ability to fine-tune voltages, monitor system stats, and adjust overclock parameters for optimal performance.

All-round energy efficiency
With the Energy Processing Unit (EPU) you'll enjoy system-wide power savings. The EPU automatically optimizes power consumption and maximizes savings with Away mode — a smart setting that creates an extreme energy-saving scenario by shutting down unused I/O controllers.

Flexible cooling controls for air or liquid
With Pro WS X299 Sage II you have comprehensive control over fans via Fan Expert 4 or our media-acclaimed UEFI. Whether you're cooling with air or water, Auto-Tuning mode intelligently configures all parameters with a single click. There's also an Extreme Quiet mode, which reduces all fan speeds to below the default minimum — keeping your system whisper-quiet when performing light tasks.

Precise digital power control
Digi+ delivers real-time control over voltage droop, switching frequency and power -efficiency settings, allowing you to fine-tune CPU voltage regulation for ultimate stability and performance.

Optimize per-core performance for every app
Intel's latest processors feature per-core tuning, and the ASUS Turbo Core app makes use of this feature by enabling you to assign applications to specific processor cores, allowing you to prioritize compute power where it's needed most.

Back to Tune it your way
Cool to the core
Effective cooling is extremely important, even at stock speeds. That is why the Pro WS X299 Sage II allows consolidated cooling control of the entire system, even for the most hardcore rigs. It comes equipped with onboard heatsinks, an array of fan headers, options for water pump and AIO headers.
- Heatsinks
- Cooler by design
Multiple Ultra-efficient heatsinks
Pro WS X299 Sage II features a thoughtful thermal design to ensure maximum performance with no CPU throttling. Its ultra-efficient VRM heatsink with a metal fin array maximizes surface area for heat dissipation, and its heatsinks and a connecting heat-pipe that's situated in the direct path of airflow combine to ensure optimal cooling performance — even under the most demanding workloads.

M.2 heatsink
Pro WS X299 Sage II features an ultra-efficient heatsink to reduce M.2 SSD temperatures for optimal storage performance and improved SSD longevity.

Back to Cool to the core
Audio & Personality
We pay careful attention to all the little details that improve your overall experience, from integrating a flashing utility directly into the UEFI to simplifying firmware updates or displaying your system vital signs. Pro WS X299 Sage II provides the tools you need to personalize your build and stay on top of things.
- Audio
- Personalization
Exclusive Codec
Realtek codec and unique design features for pristine, powerful audio

Pro WS X299 Sage II utilizes a unique audio codec designed in close collaboration with Realtek — the Realtek S1220A. It also features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and a 113dB SNR for the line-in, providing pristine audio quality. Additionally, a new impedance-sensing circuit automatically adjusts the gain to ensure optimal volume range for your headphones.

DTS:X® Ultra adds a spatial audio feature to boost headphones and speakers for an enhanced gaming, VR, and extended reality experience. DTS:X Ultra supports sound based on channels, scenes, and objects to allow for deeper sonic immersion in enabled content. It also provides post-processing enhancements and device-level tuning for DTS® codecs.
Crystal Sound 3
Flawless audio that immerses you in the game
Power pre-regulator
Reduces power-input noise to ensure consistent performance.
Audio shielding
Separates analog/digital signal domains, significantly reducing multi-lateral interference.
Separate layer for left and right tracks
Ensures minimal crosstalk between audio paths.
Integrated amplifier
Capable of driving high-impedance headphones, without rolling-off high or low frequencies.
De-pop circuit
Reduces start-up popping noise to all audio outputs.
Premium Japanese audio
Premium parts provide an immersive sound signature, with exceptional fidelity.
Back to Audio & Personality
ASUS Control Center
Pro WS X299 Sage II features ASUS Control Center (ACC), a centralized and integrated IT management platform for monitoring and controlling ASUS commercial products, including servers, workstations and digital signage. ACC enables remote BIOS updates, monitoring of multiple systems via mobile devices, and one-click software updates and dispatching, allowing easier server management for any IT infrastructure.

*Learn more about ASUS Control Center

Intel Optane memory readyIntel Optane™ is a revolutionary non-volatile memory technology supported by Pro WS X299 Sage II. Intel Optane memory modules accelerate attached storage to reduce boot and load times, so everything feels faster and more responsive.
Learn more >

Intel X299 chipsetThe Intel X299 chipset supports LGA 2066-socket Intel Core X-Series Processors. It provides improved performance by utilizing serial point-to-point links, allowing increased bandwidth and stability. Additionally, X299 provides a maximum 10 USB 3.2 Gen 1 ports, 8 SATA 6 Gbps ports and up to 32 Gbps M.2 support for faster data retrieval.

Intel® Core™ X-series processors for LGA 2066 socketIntel Core X-series processors (6-core and above): 4-channel (8-DIMM), over 48/44 PCI Express 3.0/2.0 lanes.






